Charles M Perou Selected Research

Glioma (Gliomas)

12/2015	Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents.
6/2015	Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

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Charles M Perou Research Topics

Disease

236	Neoplasms (Cancer) 04/2024 - 06/2002
216	Breast Neoplasms (Breast Cancer) 04/2024 - 10/2002
40	Triple Negative Breast Neoplasms 03/2024 - 12/2008
21	Neoplasm Metastasis (Metastasis) 08/2023 - 03/2009
20	Pathologic Complete Response 03/2024 - 08/2005
17	Carcinogenesis 01/2024 - 12/2007
7	Carcinoma (Carcinomatosis) 02/2015 - 01/2006
6	Noninfiltrating Intraductal Carcinoma (DCIS) 07/2022 - 02/2007
5	Genomic Instability 12/2022 - 06/2012
4	Melanoma (Melanoma, Malignant) 12/2021 - 10/2012
4	Disease Progression 01/2021 - 01/2010
3	Hypoxia (Hypoxemia) 04/2024 - 04/2012
3	Lung Neoplasms (Lung Cancer) 01/2016 - 03/2009
3	Squamous Cell Carcinoma of Head and Neck 08/2014 - 05/2004
3	Tics (Tic) 02/2014 - 02/2012
3	Retinoblastoma (Glioblastoma, Retinal) 03/2012 - 01/2008
2	Residual Neoplasm 01/2024 - 03/2014
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 01/2021
2	Aneuploidy (Aneuploid) 01/2020 - 01/2004
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2018 - 01/2016

Drug/Important Bio-Agent (IBA)

109	Phenobarbital (Luminal)FDA Link 03/2024 - 07/2003
66	Estrogen ReceptorsIBA 03/2024 - 01/2004
50	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 10/2002
48	RNA (Ribonucleic Acid)IBA 03/2024 - 07/2006
38	Proteins (Proteins, Gene)FDA Link 10/2023 - 08/2004
35	Biomarkers (Surrogate Marker)IBA 01/2023 - 05/2004
33	ClaudinsIBA 01/2022 - 05/2009
27	Hormones (Hormone)IBA 03/2024 - 04/2006
23	Messenger RNA (mRNA)IBA 01/2023 - 10/2002
21	Progesterone Receptors (Progesterone Receptor)IBA 01/2020 - 04/2006
15	Trastuzumab (Herceptin)FDA Link 12/2023 - 04/2012
15	Paclitaxel (Taxol)FDA LinkGeneric 11/2023 - 08/2005
14	human ERBB2 proteinIBA 12/2020 - 05/2008
13	Carboplatin (JM8)FDA LinkGeneric 10/2023 - 07/2007
12	AnthracyclinesIBA 09/2023 - 04/2007
12	ParaffinIBA 01/2023 - 12/2002
11	Formaldehyde (Formol)FDA Link 01/2023 - 01/2004
11	Estrogens (Estrogen)FDA Link 12/2021 - 04/2006
11	ErbB Receptors (EGF Receptor)IBA 01/2018 - 02/2007
10	Immune Checkpoint InhibitorsIBA 10/2023 - 01/2017
10	taxaneIBA 09/2023 - 03/2009
9	Tamoxifen FDA LinkGeneric 12/2023 - 04/2006
9	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 06/2004
8	Lapatinib (GW572016)FDA Link 11/2023 - 10/2012
8	Docetaxel (Taxotere)FDA Link 01/2023 - 03/2009
8	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 08/2005
7	MicroRNAs (MicroRNA)IBA 01/2016 - 01/2012
6	LigandsIBA 01/2016 - 08/2011
5	pertuzumabIBA 01/2023 - 08/2013
5	Protein Isoforms (Isoforms)IBA 01/2020 - 08/2014
5	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2017 - 07/2007
5	Fluorouracil (Carac)FDA LinkGeneric 04/2012 - 06/2004
5	Keratin-5 (Keratin 5)IBA 03/2008 - 12/2002
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2024 - 03/2009
4	Fulvestrant (Faslodex)FDA Link 01/2024 - 10/2013
4	EnzymesIBA 11/2020 - 01/2008
4	VimentinIBA 12/2018 - 02/2006
4	AntibodiesIBA 09/2017 - 08/2004
4	Phosphotransferases (Kinase)IBA 01/2017 - 04/2012
4	Complementary DNA (cDNA)IBA 11/2006 - 06/2002
3	Letrozole (Femara)FDA LinkGeneric 03/2024 - 08/2009
3	Anastrozole (Arimidex)FDA LinkGeneric 01/2024 - 03/2010
3	RNA Helicases (RNA Helicase)IBA 10/2023 - 01/2018
3	InterferonsIBA 10/2023 - 01/2021
3	MicellesIBA 08/2023 - 01/2016
3	Trinitrotoluene (TNT)IBA 01/2023 - 09/2010
3	ChromatinIBA 12/2021 - 01/2013
3	Transcription Factors (Transcription Factor)IBA 01/2018 - 11/2007
3	Keratins (Keratin)IBA 01/2018 - 08/2004
3	Epithelial Cell Adhesion MoleculeIBA 01/2017 - 02/2012
3	Epidermal Growth Factor (EGF)IBA 10/2015 - 06/2006
3	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 07/2015 - 06/2010
3	Cetuximab (Erbitux)FDA Link 03/2014 - 07/2007
3	Oncogene Proteins (Oncogene Protein)IBA 06/2010 - 01/2006
2	Immunoglobulin G (IgG)IBA 03/2024 - 01/2023
2	P-2 (P 2)IBA 09/2023 - 03/2009
2	Bevacizumab (Avastin)FDA Link 01/2022 - 01/2015
2	LipidsIBA 01/2022 - 09/2012
2	Small Cytoplasmic RNAIBA 12/2021 - 01/2021
2	Monoclonal AntibodiesIBA 05/2021 - 12/2002
2	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 01/2018
2	entinostat (MS 275)IBA 01/2021 - 11/2018
2	Small Interfering RNA (siRNA)IBA 11/2020 - 07/2006
2	AntigensIBA 01/2020 - 01/2017
2	Cyclin D1IBA 01/2019 - 09/2009
2	PhosphoproteinsIBA 12/2018 - 07/2013
2	PlatinumIBA 12/2018 - 01/2018
2	Estrogen Receptor alphaIBA 01/2018 - 11/2007
2	AsparagineIBA 01/2018 - 01/2018
2	Capecitabine (Xeloda)FDA Link 01/2018 - 04/2012
2	AmberIBA 01/2018 - 03/2016
2	lysophosphatidic acidIBA 04/2017 - 06/2009
2	ProteomeIBA 01/2017 - 03/2016

Therapy/Procedure

95	Therapeutics 03/2024 - 07/2006
48	Drug Therapy (Chemotherapy) 03/2024 - 08/2005
21	Neoadjuvant Therapy 03/2024 - 07/2003
9	Immunotherapy 01/2022 - 11/2016
4	Precision Medicine 01/2022 - 01/2016
4	Transplantation 09/2013 - 04/2008
3	Mammaplasty (Breast Reconstruction) 12/2023 - 11/2009